Bone Abstracts

Objectives: Patients with osteogenesis imperfecta (OI) type IA have a mild phenotype with normal or near-normal height. The addition of recombinant human GH (rhGH) to ongoing treatment with bisphosphonates can increase measures of BMD and growth. We studied growth rate bone density and bone metabolism in two girls affected by OI type IA and growth delay.Materials and methods: Eight children (six girls and two boys) with OI type IA were treated with Rised...

Objectives: The correlation between vitamin D and GH–IGF1 axis is documented. Growing children, need extra Vit-D because it is required for growth. Severe deficiency in Vit-D generates poor growth. Height is usually more affected. Growth hormone (GH) deficiency in children causes severe growth retardation, Vit-D deficiency, and osteopenia. The aim of this presentation was: 1. To evaluate the Vit-D blood level to children in substitution treatment with rhGH. 2. To see if t...

Introduction: Bisphosphonates are the most commonly prescribed type of medication for the treatment of osteoporosis. This treatment, however, is not without adverse effects. Several case reports and case series have indicated an association between a unique fracture type, so-called ‘atypical femoral fractures,’ (AFF) and prolonged bisphosphonate use.Case report: We present a 77-year-old woman with no history of trauma, or associated with low-en...